Polycystic Kidney Disease causes kidney failure, damage to other organs and sometimes premature death in children and adults. There are two forms: ADPKD - AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE - the world’s most common inherited kidney disease, in which fluid-filled cysts develop, multiply and grow in both kidneys. Other organs, e.g. the liver and brain, may be affected. Between 1 in 400-1000 people worldwide have ADPKD. Over half affected will have kidney failure by age 60. Many will experience regular pain, disability and anxiety. If someone has ADPKD, there is a 1 in 2 likelihood that the disease will pass to each child born. ARPKD - AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE - is a rare disease that affects kidneys and liver. It occurs in about 1 in 20,000 live births in the UK. ARPKD is severe. Sadly, about one baby in three with ARPKD dies from breathing problems during the first weeks after birth and some will die during pregnancy. However, 8 to 9 in ten babies who survive the first four weeks of life are still alive at five years old. Encouragingly, a many now survive into adulthood and are able to live full and productive lives.